The aim of the present paper is to show that anti-realism in science, which has arguably become more fashionable in recent years, contrary to what its proponents assert, cannot make use of quantum mechanics and its impressive achievements as a trump card in justifying its claims. I will argue that scientific anti-realism far from providing scientific community with a progressive methodological framework is as restrictive approach which would hamper scientific progress. Focusing on the historical evidence of the ways in which quantum mechanics was developed, I will further argue that the orthodox interpretation of quantum mechanics due to Bohr and Heisenberg, among others, with its in—built anti-realistic elements provides a damning verdict against the claims of anti-realists. Following a critical assessment of a number of alternative interpretations or the calculus of quantum mechanics, I shall present realistic approaches which provide more effective and fruitful conceptual frameworks for the advancement of research in the quantum world.
Keywords: Realism, Anti-realism, Quantum Mechanics, Scientific Knowledge, Copenhagen interpretation, Instrumentalism.